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505982 (-)-Quinpirole Hydrochloride - CAS 85798-08-9 - Calbiochem

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Dopamine D₂ Receptor Agonist, Quinpirole, Quinpirole, LY-171,555, LY 171555

Primary Target: D₂
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      85798-08-9C₁₃H₂₁N₃•HCl
      Description
      Overview

      This product has been discontinued.



      A potent, selective dopamine D2 receptor agonist with a Ki value of 4.8 nM. Some D3(Ki = 24 nM) and D4 (Ki = 30 nM) receptor agonistic action has also been reported. In rat striatum studies in vitro, application of quinpriole inhibited single pulse dopamine overflow in a concentration-dependent manner (IC50 = 32.5 nM).
      Catalogue Number505982
      Brand Family Calbiochem®
      SynonymsDopamine D₂ Receptor Agonist, Quinpirole, Quinpirole, LY-171,555, LY 171555
      References
      ReferencesOʹNeill, C. et al. 2009. J. Neurochem. 108, 545.
      Malmberg, A. and Mohell, N. 1995. J. Pharmacol. Exp. Ther. 274, 790.
      Seeman, P. and Schaus, J. M. 1991. Eur. J. Pharmacol. 203, 105.
      Product Information
      CAS number85798-08-9
      FormWhite powder
      Hill FormulaC₁₃H₂₁N₃•HCl
      Chemical formulaC₁₃H₂₁N₃•HCl
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetD₂
      Primary Target K<sub>i</sub>4.8 nM
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      505982 0

      Documentation

      (-)-Quinpirole Hydrochloride - CAS 85798-08-9 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Références bibliographiques

      Aperçu de la référence bibliographique
      OʹNeill, C. et al. 2009. J. Neurochem. 108, 545.
      Malmberg, A. and Mohell, N. 1995. J. Pharmacol. Exp. Ther. 274, 790.
      Seeman, P. and Schaus, J. M. 1991. Eur. J. Pharmacol. 203, 105.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2013 JSW
      SynonymsDopamine D₂ Receptor Agonist, Quinpirole, Quinpirole, LY-171,555, LY 171555
      DescriptionA potent, selective dopamine D2 receptor agonist with a Ki value of 4.8 nM. Some D3(Ki = 24 nM) and D4 (Ki = 30 nM) receptor agonistic action has also been reported. In rat striatum studies in vitro, application of quinpriole inhibited single pulse dopamine overflow in a concentration-dependent manner (IC50 = 32.5 nM).
      FormWhite powder
      CAS number85798-08-9
      Chemical formulaC₁₃H₂₁N₃•HCl
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (7.3 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesOʹNeill, C. et al. 2009. J. Neurochem. 108, 545.
      Malmberg, A. and Mohell, N. 1995. J. Pharmacol. Exp. Ther. 274, 790.
      Seeman, P. and Schaus, J. M. 1991. Eur. J. Pharmacol. 203, 105.