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263203 3,4-Dephostatin, Ethyl-

3,4-Dephostatin, Ethyl- : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: PTP1B Inhibitor II

263203
  
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      Aperçu

      Replacement Information
      Description
      Overview

      This product has been discontinued.

      We are offering 3,4-Dephostatin (Cat. No. 263202) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.





      A more stable ethyl analog of 3,4-Dephostatin (Cat. No. 263202). Potently inhibits protein tyrosine phosphatase 1B (IC50 = 3.2 µM). Degassed solvents are recommended for reconstitution.
      Catalogue Number263203
      Brand Family Calbiochem®
      SynonymsPTP1B Inhibitor II
      References
      ReferencesSuzuki, T., et al. 2001. J. Biol. Chem. 276, 27511. Watanabe, T., et al. 2000. Tetrahedron 56, 741.
      Product Information
      FormDark brown solid
      Hill FormulaC₈H₁₀N₂O₃
      Chemical formulaC₈H₁₀N₂O₃
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary Targetprotein tyrosine phosphatase 1b
      Primary Target IC<sub>50</sub>3.2 µM
      Purity≥90% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      263203 0

      Documentation

      3,4-Dephostatin, Ethyl- Certificats d'analyse

      TitreNuméro de lot
      263203

      Références bibliographiques

      Aperçu de la référence bibliographique
      Suzuki, T., et al. 2001. J. Biol. Chem. 276, 27511. Watanabe, T., et al. 2000. Tetrahedron 56, 741.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-June-2008 RFH
      SynonymsPTP1B Inhibitor II
      DescriptionA more stable analog of the protein tyrosine phosphatase (PTP) inhibitor, 3,4-Dephostatin (Cat. No. 263202). Potently inhibits PTP1B (IC50 = 3.2 µM). Reported to enhance the translocation of glucose transporter 4 (GLUT-4) from the cytoplasm to the membrane.
      FormDark brown solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₈H₁₀N₂O₃
      Structure formulaStructure formula
      Purity≥90% by HPLC
      SolubilityDMSO (50 mg/ml) or Methanol (50 mg/ml). Degassed solvents are recommended for reconstitution.
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Standard Handling
      ReferencesSuzuki, T., et al. 2001. J. Biol. Chem. 276, 27511. Watanabe, T., et al. 2000. Tetrahedron 56, 741.