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ABN1372 Anti-Potassium Channel KCNQ5 Antibody

This Anti-Potassium Channel KCNQ5 Antibody is validated for use in Immunohistochemistry and Western Blotting for the detection of Potassium Channel KCNQ5.

Anti-Potassium Channel KCNQ5 Antibody : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Neuroscience UniProt Number: Q9NR82
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ABN1372
50 µg  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RIHC, WBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN1372
      ReplacesAB5599
      DescriptionAnti-Potassium Channel KCNQ5 Antibody
      Alternate Names
      • Potassium voltage-gated channel subfamily KQT member 5
      • Potassium channel subunit alpha KvLQT5
      • KQT-like 5
      • Voltage-gated potassium channel subunit Kv7.5
      • KCNQ5
      Background InformationKCNQ5 is subunit one of a voltage gated potassium channel expressed in the brain and other tissues. KCNQ5 forms the complete channel with KCNQ3. This channel gives rise to the "M" potassium current which is a slowly activating and deactivating current. This current plays a critical role in determining the subthreshold electrical excitability of neurons. KCNQ5 is strongly expressed in the brain but also in skeletal muscle and vascular smooth muscle cells. KCNQ5 activity is also regulated via phosphorylation by PKC and that kinase regulation may be a key to regulating excitability in neurons and muscle cells.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit Polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Potassium Channel KCNQ5 Antibody is validated for use in Immunohistochemistry and Western Blotting for the detection of Potassium Channel KCNQ5.
      Key Applications
      • Immunohistochemistry
      • Western Blotting
      Application NotesWestern Blotting Analysis: A 0.1µg/mL dilution from a representative lot detected Potassium Channel KCNQ5 in 10 µg of transient over-expression of Potassium Channel KCNQ5 in HEK293 cell lysate.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the Human Potassium Channel KCNQ5.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityWestern Blotting Analysis was tested on overxpressing transfected cell lysate.
      Species Reactivity
      • Human
      • Rat
      Species Reactivity NoteHuman, Rat. Predicted to react with Canine, Feline, Rhesus Macaque, Giant Panda, Chimpanzee based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~103 kDa observed. Predicted to cross react to Isoforms 1, 2, and 3. Additional bands are detected in endogenous lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human cerebral cortex tissue.

      Imunnohistochemistry Analysis: A 1:2,000 dilution of this antibody detected Potassium Channel KCNQ5 in human cerebral cortex tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      ABN1372 04055977112610

      Documentation

      Anti-Potassium Channel KCNQ5 Antibody FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Anti-Potassium Channel KCNQ5 Antibody Certificats d'analyse

      TitreNuméro de lot
      Anti-Potassium Channel KCNQ5 Q2476155
      Anti-Potassium Channel KCNQ5 - 3093511 3093511
      Anti-Potassium Channel KCNQ5 - 3272275 3272275
      Anti-Potassium Channel KCNQ5 - 3385871 3385871
      Anti-Potassium Channel KCNQ5 - 3689950 3689950
      Anti-Potassium Channel KCNQ5 - 3904326 3904326
      Anti-Potassium Channel KCNQ5 - 4116917 4116917
      Anti-Potassium Channel KCNQ5 - 4284132 4284132