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ABT165 Anti-RAB8A Antibody

This Anti-RAB8A Antibody is validated for use in Western Blotting for the detection of RAB8A.

Anti-RAB8A Antibody : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Cell Structure Research Sub-Category: Vesicular Trafficking Gene Symbol: RAB8A, MEL, RAB8 UniProt Number: P61006
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ABT165
100 µg  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT165
      DescriptionAnti-RAB8A Antibody
      Alternate Names
      • Ras-related protein Rab-8A
      • Oncogene c-mel
      Background InformationRas-related protein Rab-8A (RAB8A) is one of two Rab8 isoforms, which belong to the superfamily of GTPases. They cycle between an active GTP-bound state, formed from interaction with guanine nucleotide exchange factors (GEFs) such as Rabin8 and GRAB; and an inactive GDP-bound state via interaction with GTPase activating proteins (GAPs) such as TBC1D1. Rab8A activates various effector molecules, which are coupled to intracellular signaling networks that mediate membrane and vesicular trafficking, and actin remodeling. Rab8A is found in the golgi network, perinuclear region, plasma membrane, lamellipodia, and cilia, among other regions.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Serum starved HeLa cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-RAB8A Antibody is validated for use in Western Blotting for the detection of RAB8A.
      Key Applications
      • Western Blotting
      Application NotesWestern Blot Analysis: A representative lot from an independent laboratory detected RAB8A in human cerebellum and brain.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human RAB8A.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-terminus of RAB8A.
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Mouse and Bovine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • RAB8A
      • MEL
      • RAB8
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~24 kDa observed. Uncharacterized bands may be observed at ~110 kDa and ~38 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in serum starved HeLa cell lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected RAB8A in serum starved HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      ABT165 04053252698804

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      Catégories

      Life Science Research > Antibodies and Assays > Primary Antibodies