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ST1041 Anti-RKIP Rabbit pAb

Anti-RKIP Rabbit pAb : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Anti-Raf Kinase Inhibitory Protein

ST1041
  
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      Host
      Rb
      Description
      Overview

      This product has been discontinued.





      Recognizes the ~23 kDa raf kinase inhibitory protein (RKIP) in H19-7 cells.
      Catalogue NumberST1041
      Brand Family Calbiochem®
      SynonymsAnti-Raf Kinase Inhibitory Protein
      Application Data
      Detection of rat, mouse and human RKIP by immunoblotting. Samples: whole cell lysate from rat cells (lane 1), human cells (lane 2), and mouse cells (lane 3). Primary antibody: Anti-RKIP Rabbit pAb (Cat. No. ST1041) (1:1000). Detection: chemiluminescence.
      References
      ReferencesCorbit, K.C et al. 2003. J. Biol. Chem. 278,13061.
      Nishizuka, Y. 1992. Science 258, 607.
      Product Information
      FormLiquid
      FormulationUndiluted serum.
      Positive controlH19-7 cells
      PreservativeNone
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Immunocytochemistry
      Application NotesImmunoblotting (1:2000-1:5000)
      Immunocytochemistry (1:500-1:2000)
      Application CommentsAntibody should be titrated for optimal results in individual systems.
      Biological Information
      Immunogenfull-length, recombinant rat RKIP fused to GST
      ImmunogenRat
      HostRabbit
      IsotypeIgG
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      ST1041 0

      Documentation

      Anti-RKIP Rabbit pAb Certificats d'analyse

      TitreNuméro de lot
      ST1041

      Références bibliographiques

      Aperçu de la référence bibliographique
      Corbit, K.C et al. 2003. J. Biol. Chem. 278,13061.
      Nishizuka, Y. 1992. Science 258, 607.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-October-2007 RFH
      SynonymsAnti-Raf Kinase Inhibitory Protein
      ApplicationImmunoblotting (1:2000-1:5000)
      Immunocytochemistry (1:500-1:2000)
      Application Data
      Detection of rat, mouse and human RKIP by immunoblotting. Samples: whole cell lysate from rat cells (lane 1), human cells (lane 2), and mouse cells (lane 3). Primary antibody: Anti-RKIP Rabbit pAb (Cat. No. ST1041) (1:1000). Detection: chemiluminescence.
      DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~23 kDa raf kinase inhibitory protein (RKIP).
      BackgroundThe PKC family of serine/threonine kinases plays a key role in physiological processes such as growth, death, differentiation, and transformation. It has been shown that one means by which PKCs activate Raf-1 signaling to ERK involves the loss of inhibition by RKIP. Although PKCs have been well established as activators of MAP kinases, their targets in this pathway are still unknown. The mechanism of PKC-mediated Raf/MAP kinase activation is of major importance since several components of the MAP kinase pathway are mutated in human cancers.
      HostRabbit
      Immunogen speciesRat
      Immunogenfull-length, recombinant rat RKIP fused to GST
      IsotypeIgG
      Specieshuman, monkey, mouse, rat
      Positive controlH19-7 cells
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      CommentsAntibody should be titrated for optimal results in individual systems.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesCorbit, K.C et al. 2003. J. Biol. Chem. 278,13061.
      Nishizuka, Y. 1992. Science 258, 607.