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ABD104 Anti-SnoN Antibody

This Anti-SnoN Antibody is validated for use in Western Blotting and Immunocytochemistry and Immunohistochemistry for the detection of SnoN.

Anti-SnoN Antibody : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation Gene Symbol: SKIL, SNO UniProt Number: P12757
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ABD104
100 µg  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICC, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABD104
      DescriptionAnti-SnoN Antibody
      Alternate Names
      • Ski-like protein
      • Ski-related oncogene
      • Ski-related protein
      • SnoN
      Background InformationThe Ski family of oncogenes includes Ski and Sno (Ski-related novel gene, or Ski-like). Ski family members are nuclear proteins that form homodimers and heterodimers, bind to DNA and function as transcriptional activators and repressors. The Ski proteins regulate TGFß induced gene-specific transcriptional activation by effectively repressing Smad activity and, thereby, inhibit TGFß induced cell growth and extracellular matrix production. Recently, SnoN has been shown to maintain pluripotency through selective repression of mesendodermal genes in human ES cells.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit Polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-SnoN Antibody is validated for use in Western Blotting and Immunocytochemistry and Immunohistochemistry for the detection of SnoN.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesImmunohistochemical Analysis: A 1:50 dilution of this antibody detected SnoN in human skeletal muscle myocytes. Immunohistochemical Analysis: A 1:50 dilution of this antibody detected SnoN in human lung tissue.
      Immunocytochemicaly Analysis: A 1:100 dilution of this antibody detected SnoN in H9 human embryonic stem cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to amino acids 358-372 of human SnoN protein.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SKIL
      • SNO
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~80 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in a human placenta tissue lysate. Western Blot Analysis: 1 μg/ml of this antibody detected SnoN in a 10μg of human placenta tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      ABD104 04053252986444