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504842 CGP 37849 - CAS 127910-31-0 - Calbiochem

CGP 37849 - CAS 127910-31-0 - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: (E)-(±)-2-Amino-4-methyl-5-phosphono­-3-pentenoic acid

Primary Target: NMDA receptors
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      127910-31-0C₆H₁₂NO₅P
      Description
      OverviewA highly potent competitive antagonist selective for NMDA receptors (Ki = 35 nM). Biologically viable admitted orally or systematically. Widely used in studies of epilepsy, schizophrenia, depression, stress and anxiety related mental disorders.
      Catalogue Number504842
      Brand Family Calbiochem®
      Synonyms(E)-(±)-2-Amino-4-methyl-5-phosphono­-3-pentenoic acid
      References
      ReferencesSerafini, G., et al. 2013. Curr. Pharmaceut. Design 19, 1898.
      Szewczyk, B., et al. 2012. Expert. Op. Invest. Drugs 21, 91.
      Przegalinski, E., et al. 2000. Neuropharmacol. 39, 1858.
      Maj, J., et al. 1993. Polish J. Pharmacol. 45, 455.
      Fagg, E., et al. 1990. Br. J. Pharmacol. 99, 791.
      Schmutz, M., et al. 1990. Naunyn-Schmiedebergʹs Arch. Pharmacol. 342, 61.
      Product Information
      CAS number127910-31-0
      FormWhite solid
      Hill FormulaC₆H₁₂NO₅P
      Chemical formulaC₆H₁₂NO₅P
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetNMDA receptors
      Primary Target K<sub>i</sub>35 nM
      Purity≥99% by Chiral HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      504842 0

      Documentation

      CGP 37849 - CAS 127910-31-0 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Références bibliographiques

      Aperçu de la référence bibliographique
      Serafini, G., et al. 2013. Curr. Pharmaceut. Design 19, 1898.
      Szewczyk, B., et al. 2012. Expert. Op. Invest. Drugs 21, 91.
      Przegalinski, E., et al. 2000. Neuropharmacol. 39, 1858.
      Maj, J., et al. 1993. Polish J. Pharmacol. 45, 455.
      Fagg, E., et al. 1990. Br. J. Pharmacol. 99, 791.
      Schmutz, M., et al. 1990. Naunyn-Schmiedebergʹs Arch. Pharmacol. 342, 61.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-July-2013 JSW
      Synonyms(E)-(±)-2-Amino-4-methyl-5-phosphono­-3-pentenoic acid
      DescriptionA highly potent competitive antagonist selective for NMDA receptors (Ki = 35 nM). Biologically viable admitted orally or systematically. Widely used in studies of epilepsy, schizophrenia, depression, stress and anxiety related mental disorders.
      FormWhite solid
      CAS number127910-31-0
      Chemical formulaC₆H₁₂NO₅P
      Structure formulaStructure formula
      Purity≥99% by Chiral HPLC
      SolubilityH₂O (100 mM). Slight warming is required for complete solubilization.
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSerafini, G., et al. 2013. Curr. Pharmaceut. Design 19, 1898.
      Szewczyk, B., et al. 2012. Expert. Op. Invest. Drugs 21, 91.
      Przegalinski, E., et al. 2000. Neuropharmacol. 39, 1858.
      Maj, J., et al. 1993. Polish J. Pharmacol. 45, 455.
      Fagg, E., et al. 1990. Br. J. Pharmacol. 99, 791.
      Schmutz, M., et al. 1990. Naunyn-Schmiedebergʹs Arch. Pharmacol. 342, 61.