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234503 Compound 52

A potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC₅₀ = 7 µM), and the related Pho85p kinase (IC₅₀ = 2 µM).

Compound 52 : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine

Primary Target: Cdc28p
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      212779-48-1C₁₆H₁₉ClN₆O
      Description
      Overview

      This product has been discontinued.





      A potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC50 = 7 µM), and the related Pho85p kinase (IC50 = 2 µM).
      Catalogue Number234503
      Brand Family Calbiochem®
      Synonyms2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine
      References
      ReferencesGray, N.S., et al. 1998. Science 281, 533.
      Product Information
      CAS number212779-48-1
      DeclarationSold under license of U.S. Patents 6,617,331 and 6,803,371.
      FormOff-white solid
      Hill FormulaC₁₆H₁₉ClN₆O
      Chemical formulaC₁₆H₁₉ClN₆O
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetCdc28p
      Primary Target IC<sub>50</sub>7 µM
      Secondary targetPho85p kinase (IC₅₀ = 2 µM)
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 40

      Limited evidence of a carcinogenic effect.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      234503 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Compound 52 FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Compound 52 Certificats d'analyse

      TitreNuméro de lot
      234503

      Références bibliographiques

      Aperçu de la référence bibliographique
      Gray, N.S., et al. 1998. Science 281, 533.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision29-December-2009 RFH
      Synonyms2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine
      DescriptionA potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p (IC50 = 7 µM) and the related Pho85p kinase (IC50 = 2 µM).
      FormOff-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number212779-48-1
      Chemical formulaC₁₆H₁₉ClN₆O
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (200 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Carcinogenic / Teratogenic
      ReferencesGray, N.S., et al. 1998. Science 281, 533.