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324905 Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem

A cell-permeable antitumor antibiotic.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 4ʹ-Epidoxorubicin, HCl

Primary Target: Antitumor antibiotic
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      56390-09-1C₂₇H₂₉NO₁₁ · HCl
      Description
      Overview

      This product has been discontinued.



      A cell-permeable antitumor antibiotic. A stereoisomer of Doxorubicin (Cat. No. 324380) that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.
      Catalogue Number324905
      Brand Family Calbiochem®
      Synonyms4ʹ-Epidoxorubicin, HCl
      References
      ReferencesLuck, H.J., et al. 1996. Semin. Oncol. 23, 33.
      Sandri, M.I., et al. 1996. Br. J. Cancer 73, 1518.
      Boddy, A.V., et al. 1995. Eur. J. Cancer 31A, 69.
      Pouna, P., et al. 1995. Cancer. Chemother. Pharmacol. 35, 257.
      Product Information
      CAS number56390-09-1
      ATP CompetitiveN
      FormOrange-red solid
      Hill FormulaC₂₇H₂₉NO₁₁ · HCl
      Chemical formulaC₂₇H₂₉NO₁₁ · HCl
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAntitumor antibiotic
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSQI9295750
      Safety Information
      R PhraseR: 20/21/22-40

      Harmful by inhalation, in contact with skin and if swallowed.
      Limited evidence of a carcinogenic effect.
      S PhraseS: 22-36

      Do not breathe dust.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      324905 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      324905

      Références bibliographiques

      Aperçu de la référence bibliographique
      Luck, H.J., et al. 1996. Semin. Oncol. 23, 33.
      Sandri, M.I., et al. 1996. Br. J. Cancer 73, 1518.
      Boddy, A.V., et al. 1995. Eur. J. Cancer 31A, 69.
      Pouna, P., et al. 1995. Cancer. Chemother. Pharmacol. 35, 257.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-May-2008 RFH
      Synonyms4ʹ-Epidoxorubicin, HCl
      DescriptionA cell-permeable, antitumor antibiotic. A stereoisomer of doxorubicin that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.
      FormOrange-red solid
      CAS number56390-09-1
      RTECSQI9295750
      Chemical formulaC₂₇H₂₉NO₁₁ · HCl
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful & Carcinogenic / Teratogenic
      Merck USA index14, 3623
      ReferencesLuck, H.J., et al. 1996. Semin. Oncol. 23, 33.
      Sandri, M.I., et al. 1996. Br. J. Cancer 73, 1518.
      Boddy, A.V., et al. 1995. Eur. J. Cancer 31A, 69.
      Pouna, P., et al. 1995. Cancer. Chemother. Pharmacol. 35, 257.