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505311 Gallamine Triethiodide - CAS 65-29-2 - Calbiochem

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 2,2ʹ,2ʹʹ-(benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethanaminium) iodide, Muscarinic Receptor Antagonist, Gallamine Triethiodide, Muscarinic mAChR Antagonist, Gallamine Triethiodide

Primary Target: mAChR
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      65-29-2C₃₀H₆₀I₃N₃O₃
      Description
      Overview

      This product has been discontinued.



      A negative allosteric modulator selective for muscarinic AChRs. Most selective for M2 receptors (Ki = 2.4 nM) over other mAChRs (M2 > M1 = M4 > M3 = M5). Used to study the roles of M2 receptors in neuromuscular transmission and neuroimmunology.
      Catalogue Number505311
      Brand Family Calbiochem®
      Synonyms2,2ʹ,2ʹʹ-(benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethanaminium) iodide, Muscarinic Receptor Antagonist, Gallamine Triethiodide, Muscarinic mAChR Antagonist, Gallamine Triethiodide
      References
      ReferencesBeltrame, P., 2011. Clin. Exp. Immunol. 164, 170.
      Gnagey, A., et al., 1999. Mol. Pharmacol. 56, 1245.
      Leppik, A., et al. 1994. Mol. Pharmacol. 45, 983.
      Burke, E., 1986. Mol. Pharmacol. 30, 58.
      Product Information
      CAS number65-29-2
      FormWhite powder
      Hill FormulaC₃₀H₆₀I₃N₃O₃
      Chemical formulaC₃₀H₆₀I₃N₃O₃
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetmAChR
      Primary Target K<sub>i</sub>2.4 nM
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      505311 0

      Documentation

      Gallamine Triethiodide - CAS 65-29-2 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Références bibliographiques

      Aperçu de la référence bibliographique
      Beltrame, P., 2011. Clin. Exp. Immunol. 164, 170.
      Gnagey, A., et al., 1999. Mol. Pharmacol. 56, 1245.
      Leppik, A., et al. 1994. Mol. Pharmacol. 45, 983.
      Burke, E., 1986. Mol. Pharmacol. 30, 58.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-July-2013 JSW
      Synonyms2,2ʹ,2ʹʹ-(benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethanaminium) iodide, Muscarinic Receptor Antagonist, Gallamine Triethiodide, Muscarinic mAChR Antagonist, Gallamine Triethiodide
      DescriptionA negative allosteric modulator selective for muscarinic AChRs. Most selective for M2 receptors (Ki = 2.4 nM) over other mAChRs (M2 > M1 = M4 > M3 = M5). Used to study the roles of M2 receptors in neuromuscular transmission and neuroimmunology.
      FormWhite powder
      CAS number65-29-2
      Chemical formulaC₃₀H₆₀I₃N₃O₃
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityH₂O (100 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesBeltrame, P., 2011. Clin. Exp. Immunol. 164, 170.
      Gnagey, A., et al., 1999. Mol. Pharmacol. 56, 1245.
      Leppik, A., et al. 1994. Mol. Pharmacol. 45, 983.
      Burke, E., 1986. Mol. Pharmacol. 30, 58.