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855068 Hydroxymethyl polystyrene (100-200 mesh), 1% DVB

Novabiochem®

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Nº CAS: 9003-70-7
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855068
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Replacement Information

Tableau de caractéristiques principal

CAS #
9003-70-7
Description
Référence855068
Replaces01-64-0110
Famille de marques Novabiochem®
Alternate Names
  • Polystyrene-CH2OH (100-200 mesh)
Informations généralesThis resin is ideal for the solid phase immobilization of carboxylic acids. Less cross-linking is observed than with Merrifield resin during the attachment of diacids [1]. Reaction with a suitable phosgene equivalent converts this resin to a support suitable for the immobilization of amines [2].

Release of carboxylic acids from this support is normally effected by treatment of the resin with HF or TFMSA, or by hydrogenolysis [3]. Alcohols can be liberated by reduction with DIBAL [4] or LiBH4 [5]. Methyl esters can be produced by transesterification with MeONa [6] or Ti(OEt)4/C2H5CO2Me [7]. Carboxamides are also accessible via Lewis acid catalyzed aminolysis [8].

The product number for this product was previously 01-64-0110.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
Références bibliographiques
Informations produit
Numéro CAS9003-70-7
Code SH3903 90 90
Image de la formule structuraleImage de la formule structurale
Quality LevelMQ200
Applications
Informations biologiques
Informations physico-chimiques
Dimensions
Informations sur les matériaux
Informations toxicologiques
Informations de sécurité selon le SGH
Classe de stockage10 - 13 Autres liquides ou matières solides
WGKWGK 1 pollue faiblement l'eau
Informations sur la sécurité
Notifications sur l'utilisation du produit
Informations relatives au stockage et à l'expédition
StockageConserver au-dessous de +30°C.
Informations sur l'emballage
Informations sur le transport
Information complémentaire
Caractéristiques
Color (visual)white to yellow to beige
Appearance of substance (visual)beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin)0.60 - 1.60 mmol/g
Swelling Volume (in DMF)lot specific result
The polymer matrix is copoly (styrene - 1% DVB) 100 -200 mesh

Documentation

Hydroxymethyl polystyrene (100-200 mesh), 1% DVB FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Citations

Titre
  • [1] J. M. Goldwasser, et al. (1978) Can. J. Chem., 56, 1562.
  • [2] D. J. Burdick, et al. (1993) Tetrahedron Lett., 34, 2589.
  • [3] J. M. Schlatter, et al. (1977) Tetrahedron Lett., 2851.
  • [4] M. J. Kurth, et al. (1994) J. Org. Chem., 59, 5862.
  • [5] J. M. Stewart & J. D. Young in 'Solid Phase Peptide Synthesis, 2nd Ed.', Rockford, Illinois, Pierce Chemical Company, 1984, pp. 92.
  • [6] R. Frenette, et al. (1994) Tetrahedron Lett., 35, 9177.
  • [7] L. T. Tietze & A. Steinmetz (1996) Angew. Chem. Int. Ed. Engl., 35, 651.
  • [8] D. R. Barn, et al. (1996) Tetrahedron Lett., 37, 3213.