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539560 PKC Inhibitor Peptide 19-36

The PKC Inhibitor Peptide 19-36 controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

PKC Inhibitor Peptide 19-36 : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Protein Kinase C Inhibitor Peptide 19-36, RFARKGALRQKNVHEVKN

Primary Target: PKC
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      Empirical Formula
      C₉₃H₁₅₉N₃₅O₂₄
      Description
      Overview

      This product has been discontinued.



      Acts as pseudosubstrate by binding to the active sites of protein kinase C. A potent, reversible, and substrate competitive inhibitor of protein kinase C (Ki = 147 nM) but not of protein kinase A (IC50 = 423 µM).
      Catalogue Number539560
      Brand Family Calbiochem®
      SynonymsProtein Kinase C Inhibitor Peptide 19-36, RFARKGALRQKNVHEVKN
      References
      ReferencesMakowske, M. and Rosen, O.M. 1989. J. Biol. Chem. 264, 16155.
      House, C. and Kemp, B.E. 1987. Science 238, 1726.
      Product Information
      ATP CompetitiveN
      FormWhite to off-white lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₉₃H₁₅₉N₃₅O₂₄
      Chemical formulaC₉₃H₁₅₉N₃₅O₂₄
      Hygroscopic Hygroscopic
      ReversibleY
      Sold on the basis of peptide contentY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKC
      Primary Target K<sub>i</sub>147 nM against protein kinase C
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide ContentY
      Peptide SequenceH-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-His-Glu-Val-Lys-Asn-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 weeks at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      539560 0

      Documentation

      PKC Inhibitor Peptide 19-36 FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      PKC Inhibitor Peptide 19-36 Certificats d'analyse

      TitreNuméro de lot
      539560

      Références bibliographiques

      Aperçu de la référence bibliographique
      Makowske, M. and Rosen, O.M. 1989. J. Biol. Chem. 264, 16155.
      House, C. and Kemp, B.E. 1987. Science 238, 1726.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-January-2010 RFH
      SynonymsProtein Kinase C Inhibitor Peptide 19-36, RFARKGALRQKNVHEVKN
      DescriptionActs as pseudosubstrate by binding to the active sites of protein kinase C. A potent, reversible, and substrate competitive inhibitor of protein kinase C (Ki = 147 nM) but not of protein kinase A (IC50 = 423 µM).
      FormWhite to off-white lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₉₃H₁₅₉N₃₅O₂₄
      Peptide SequenceH-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-His-Glu-Val-Lys-Asn-OH
      Purity≥95% by HPLC
      SolubilityH₂O (0.1%)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 weeks at -20°C.
      Toxicity Standard Handling
      ReferencesMakowske, M. and Rosen, O.M. 1989. J. Biol. Chem. 264, 16155.
      House, C. and Kemp, B.E. 1987. Science 238, 1726.