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539808 PRL-3 Inhibitor - CAS 893449-38-2 - Calbiochem

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 1-(2-Bromobenzyloxy)-4-bromo-2-benzylidene rhodanine

Primary Target: hPRL-3
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      893449-38-2C₁₇H₁₁Br₂NO₂S₂
      Description
      Overview

      This product has been discontinued.



      A cell-permeable benzylidene rhodanine compound that potently inhibits hPRL-3 (IC50 = 900 nM), a member of the regenerating liver family tyrosine phosphatases. Shown to reduce the invasiveness of murine melanoma B16F10 cells.
      Catalogue Number539808
      Brand Family Calbiochem®
      Synonyms1-(2-Bromobenzyloxy)-4-bromo-2-benzylidene rhodanine
      References
      ReferencesAhn, J.H., et al. 2006. Bioorg. Med. Chem. Lett. 16, 2996.
      Product Information
      CAS number893449-38-2
      ATP CompetitiveN
      FormYellow solid
      Hill FormulaC₁₇H₁₁Br₂NO₂S₂
      Chemical formulaC₁₇H₁₁Br₂NO₂S₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargethPRL-3
      Primary Target IC<sub>50</sub>900 nM against hPRL-3
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      539808 0

      Documentation

      PRL-3 Inhibitor - CAS 893449-38-2 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      PRL-3 Inhibitor - CAS 893449-38-2 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      539808

      Références bibliographiques

      Aperçu de la référence bibliographique
      Ahn, J.H., et al. 2006. Bioorg. Med. Chem. Lett. 16, 2996.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-April-2011 RFH
      Synonyms1-(2-Bromobenzyloxy)-4-bromo-2-benzylidene rhodanine
      DescriptionA cell-permeable benzylidene rhodanine compound that potently inhibits hPRL-3 (IC50 = 900 nM), a member of the regenerating liver family tyrosine phosphatases. Shown to reduce the invasiveness of murine melanoma B16F10 cells.
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number893449-38-2
      Chemical formulaC₁₇H₁₁Br₂NO₂S₂
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (5 mg/ml). Slight warming may be necessary for complete solubilization.
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful
      ReferencesAhn, J.H., et al. 2006. Bioorg. Med. Chem. Lett. 16, 2996.