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662098 UbcH5c Conjugating Enzyme E2, Human, Recombinant, E. coli

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: UBD2D3, Ubiquitin-conjugating enzyme E2 D3

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      Aperçu

      Replacement Information
      Description
      OverviewFull-length, recombinant, human UbcH5c expressed in E. coli. UbcH5c, an E2 ubiquitin ligase, is highly homologous to the yeast UbC4/5 family of E2 enzymes. UbcH5c, together with UbcH5a and UbcH5b, are the most active class of E2 enzymes in cell extracts and are associated with regulation of transcription factors such as p53, NF-κB3, and c-Fos. The active enzyme is useful in the study of ubiquitin regulation and inhibitor screening.
      Catalogue Number662098
      Brand Family Calbiochem®
      SynonymsUBD2D3, Ubiquitin-conjugating enzyme E2 D3
      References
      ReferencesBrzovic, P.S., et al. 2006. Cell Cycle 5, 2867.
      Gehrke, S.G., et al. 2003 Blood. 101, 3288.
      Nuber, U., And Scheffner, M., 1999. J. Biol. Chem. 274, 7576.
      Schwarz, S.E., et al. 1998. J. Biol. Chem. 273, 12148.
      Jensen, J., et al. 1995. J. Biol. Chem. 270, 30408.
      Scheffner, M., et al. 1994. Proc. Natl. Acad. Sci. 91, 8797.
      Product Information
      FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.0.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      662098 0

      Documentation

      UbcH5c Conjugating Enzyme E2, Human, Recombinant, E. coli FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      UbcH5c Conjugating Enzyme E2, Human, Recombinant, E. coli Certificats d'analyse

      TitreNuméro de lot
      662098

      Références bibliographiques

      Aperçu de la référence bibliographique
      Brzovic, P.S., et al. 2006. Cell Cycle 5, 2867.
      Gehrke, S.G., et al. 2003 Blood. 101, 3288.
      Nuber, U., And Scheffner, M., 1999. J. Biol. Chem. 274, 7576.
      Schwarz, S.E., et al. 1998. J. Biol. Chem. 273, 12148.
      Jensen, J., et al. 1995. J. Biol. Chem. 270, 30408.
      Scheffner, M., et al. 1994. Proc. Natl. Acad. Sci. 91, 8797.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision22-May-2009 JSW
      SynonymsUBD2D3, Ubiquitin-conjugating enzyme E2 D3
      DescriptionFull-length, recombinant, human UbcH5c expressed in E. coli. UbcH5c, an E2 ubiquitin ligase, is highly homologous to the yeast UbC4/5 family of E2 enzymes. UbcH5c, together with UbcH5a and UbcH5b, are the most active class of E2 enzymes in cell extracts and are associated with regulation of transcription factors such as p53, NF-κB3, and c-Fos. The active enzyme is useful in the study of ubiquitin regulation and inhibitor screening.
      FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.0.
      Concentration Label Please refer to vial label for lot-specific concentration
      Recommended reaction conditionsTypical concentration for conjugate formation: 100 nM to 1 µM depending on the conditions
      Purity≥95% by SDS-PAGE
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesBrzovic, P.S., et al. 2006. Cell Cycle 5, 2867.
      Gehrke, S.G., et al. 2003 Blood. 101, 3288.
      Nuber, U., And Scheffner, M., 1999. J. Biol. Chem. 274, 7576.
      Schwarz, S.E., et al. 1998. J. Biol. Chem. 273, 12148.
      Jensen, J., et al. 1995. J. Biol. Chem. 270, 30408.
      Scheffner, M., et al. 1994. Proc. Natl. Acad. Sci. 91, 8797.