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484235 p-Nitroblue Tetrazolium Chloride - CAS 298-83-9 - Calbiochem

p-Nitroblue Tetrazolium Chloride, CAS 298-83-9, is a NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: NBT, Nitro BT

Primary Target: NOS
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      298-83-9C₄₀H₃₀Cl₂N₁₀O₆
      Description
      OverviewNADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions. Useful as a substrate for alkaline phosphatase, often in conjunction with BCIP (Cat. No. 203788).
      Catalogue Number484235
      Brand Family Calbiochem®
      SynonymsNBT, Nitro BT
      References
      ReferencesPistelli, A., et al. 1994. Biochem. Pharmacol. 47, 1737.
      De la Fuente, M., et al. 1993. Comp. Immunol. Microbiol. Infect. Dis. 16, 29.
      Libon, C., et al. 1993. J. Leukoc. Biol. 53, 93.
      Mittal, C.K. 1993. Biochem. Biophys. Res. Commun. 193, 126.
      Nichols, K., et al. 1992. Neuroscience 51, 791.
      Nichols, K., et al. 1992. Neuroscience 51, 791.
      Product Information
      CAS number298-83-9
      FormYellow crystalline solid
      Hill FormulaC₄₀H₃₀Cl₂N₁₀O₆
      Chemical formulaC₄₀H₃₀Cl₂N₁₀O₆
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Applicationp-Nitroblue Tetrazolium Chloride, CAS 298-83-9, is a NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions.
      Biological Information
      Primary TargetNOS
      Primary Target IC<sub>50</sub>3-4 µM
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSXF8045000
      Safety Information
      R PhraseR: 20/21/22-68

      Harmful by inhalation, in contact with skin and if swallowed.
      Possible risks of irreversible effects.
      S PhraseS: 22-26-36/37

      Do not breathe dust.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing and gloves.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      484235 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      p-Nitroblue Tetrazolium Chloride - CAS 298-83-9 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      p-Nitroblue Tetrazolium Chloride - CAS 298-83-9 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      484235

      Références bibliographiques

      Aperçu de la référence bibliographique
      Pistelli, A., et al. 1994. Biochem. Pharmacol. 47, 1737.
      De la Fuente, M., et al. 1993. Comp. Immunol. Microbiol. Infect. Dis. 16, 29.
      Libon, C., et al. 1993. J. Leukoc. Biol. 53, 93.
      Mittal, C.K. 1993. Biochem. Biophys. Res. Commun. 193, 126.
      Nichols, K., et al. 1992. Neuroscience 51, 791.
      Nichols, K., et al. 1992. Neuroscience 51, 791.

      Brochure

      Titre
      Pathways and Biomarkers of Oxidative Stress
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-August-2008 RFH
      SynonymsNBT, Nitro BT
      DescriptionNADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions. Useful as a substrate for alkaline phosphatase, often in conjunction with BCIP (Cat. No. 203788).
      FormYellow crystalline solid
      CAS number298-83-9
      RTECSXF8045000
      Chemical formulaC₄₀H₃₀Cl₂N₁₀O₆
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityMeOH or H₂O
      Storage Protect from light
      +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage.
      Toxicity Harmful
      ReferencesPistelli, A., et al. 1994. Biochem. Pharmacol. 47, 1737.
      De la Fuente, M., et al. 1993. Comp. Immunol. Microbiol. Infect. Dis. 16, 29.
      Libon, C., et al. 1993. J. Leukoc. Biol. 53, 93.
      Mittal, C.K. 1993. Biochem. Biophys. Res. Commun. 193, 126.
      Nichols, K., et al. 1992. Neuroscience 51, 791.
      Nichols, K., et al. 1992. Neuroscience 51, 791.